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    <title>Rolle der Arginin-Biosynthese bei der Salzstressantwort von Clostridium acetobutylicum</title>
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  <abstract type="Summary">Die Salzstressantwort von Clostridium acetobutylicum wurde untersucht, um Schutzsubstanzen und Schlüsselgene zur Erhöhung der Butanolbildung in salzhaltigem Medium zu identifizieren. Arginin zeigte einen positiven Effekt auf das Wachstum unter Salzstress. Die Argininbiosynthese von C. acetobutylicum wurde durch Inaktivierung des entsprechenden Repressors gesteigert und die Butanolbildung signifikant erhöht. Transkriptomdaten zeigten eine Vernetzung der Aminosäurebiosynthesen und Stressantworten in C. acetobutylicum. Dies bietet  Ansatzpunkte für die weitere Optimierung der Butanolfermentation.&lt;ger&gt;</abstract>
  <abstract type="Summary">The salt stress response of Clostridium acetobutylicum was analyzed to identify protective substances and key genes to increase solvent formation in saline medium. Arginine showed a positive effect on growth under salt stress. The arginine biosynthesis of C. acetobutylicum was enhanced by inactivating the corresponding repressor, significantly increasing butanol production. The transcriptome revealed interlinked amino acid biosyntheses and a connection between different stress responses in C. acetobutylicum, offering starting points for the further optimization of biobutanol fermentation.&lt;eng&gt;</abstract>
  <note type="statement of responsibility">vorgelegt von Maria Lehmann</note>
  <note>GutachterInnen: Hubert Bahl (Universität Rostock, Institut für Biowissenschaften) ; Martin Hagemann (Universität Rostock, Institut für Biowissenschaften)</note>
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      <title>Die Rolle der Arginin-Biosynthese bei der Salzstressantwort von Clostridium acetobutylicum</title>
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