Stressors modulating granulosa cell functionality, ovulation and oocyte competence in bovines
Sharma, Arpna
1987-
VerfasserIn
aut
Braun, Beate
1974-
AkademischeR BetreuerIn
dgs
Pfarrer, Christiane
AkademischeR BetreuerIn
dgs
Vanselow, Jens
1960-
AkademischeR BetreuerIn
dgs
Universität Rostock
Grad-verleihende Institution
dgg
Universität Rostock
Mathematisch-Naturwissenschaftliche Fakultät
Grad-verleihende Institution
dgg
text
theses
Text
Hochschulschrift
gw
2020
monographic
XA-DE
Rostock
Universität Rostock
publisher
2020
Rostock
Universitätsbibliothek
distributor
eng
1 Online-Ressource
Ovarian follicles are exposed to stressors such as higher levels of non-esterified free fatty acids (NEFAs) or hypoxia. High follicular levels of NEFA severely affect granulosa cells (GCs) by targeting key genes of estradiol biosynthesis. Cultured GCs exposed to hypoxia showed specific regulation of genes that initiate luteinization. These effects were partly mediated by hypoxia inducible factor1 (HIF1). Thus, ovarian follicles are susceptible to elevated NEFA levels, but cope up with severe hypoxia prevailing during late folliculogenesis through specific transcription factors such as HIF1.<eng>
vorgelegt von ARPNA Sharma
Enthält Zeitschriftenartikel
GutachterInnen: Beate Brown (Reproductive Biology, Leibniz Institute for Zoo and Wildlife Research (IZW) Berlin) ; Christiane Pastor (Veterinary University Hannover, Anatomical Institute) ; Jens Vanselow (Leibniz Institute for Livestock Biology (FBN) Dummerstorf)
Dissertation Universität Rostock 2021 Kumulative Dissertation
570
ZD 32100
48.60
http://purl.uni-rostock.de/rosdok/id00002985
https://doi.org/10.18453/rosdok_id00002985
https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002985-6
https://d-nb.info/1293533955/34
Stressors modulating granulosa cell functionality, ovulation and oocyte competence in bovines
Rostock, 2020
Druck-Ausgabe
(DE-627)1752657675
Sharma, Arpna, 1987 -
urn:nbn:de:gbv:28-rosdok_id00002985-6
10.18453/rosdok_id00002985
1244452130
rda
DE-627
210324
1752313488
20251226T192822.0
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