Differentiation and survival of human neural progenitor cells in 3D scaffolds of self-assembling peptide hydrogels
Liedmann, Andrea
1979-
VerfasserIn
aut
Rolfs, Arndt
1959-
AkademischeR BetreuerIn
dgs
Kuznetsov, Sergei A.
AkademischeR BetreuerIn
dgs
Wree, Andreas
1952-
AkademischeR BetreuerIn
dgs
Universität Rostock
Grad-verleihende Institution
dgg
Universität Rostock
Mathematisch-Naturwissenschaftliche Fakultät
Grad-verleihende Institution
dgg
text
theses
Text
Hochschulschrift
gw
2013
monographic
XA-DE
Rostock
Universität
publisher
2013
Rostock
Universitätsbibliothek
distributor
eng
1 Online-Ressource
In this project we used a human neural progenitor cell line (hNPCs), whereat the cells were embedded in the synthetic self-assembling peptide hydrogel and modified formulations. Different protocols of culture conditions (2D versus 3D) were compared to analyze the neuronal differentiation and survival of the cells. The hydrogels enhance the neuronal differentiation of the hNPCs of about 2.3 fold, with an additional increase of about 2,5 fold more for the modified Scaffolds. Additionally the hNPCs were protected from apoptosis and accordingly survived longer when encapsulated in 3D scaffolds.<eng>
vorgelegt von Andrea Liedmann
GutachterInnen: Arndt Rolfs (Universität Rostock, Albrecht-Kossel-Institut für Neuroregeneration (AKos), Zentrum für Nervenheilkunde) ; Sergei A. Kuznetsov (Institut für Zellbiologie und Biosystemtechnik, Fachbereich Biowissenschaften) ; A. Wree (Universitätsmedizin Rostock, Institut für Anatomie)
Dissertation Universität Rostock 2013
610
570
WW 3880
WX 6640
42.15
44.90
http://purl.uni-rostock.de/rosdok/id00002503
Differentiation and survival of human neural progenitor cells in 3D scaffolds of self-assembling peptide hydrogels
Rostock : Universität, 2013
Druck-Ausgabe
(DE-627)1670228428
Liedmann, Andrea, 1979 -
urn:nbn:de:gbv:28-rosdok_id00002503-3
10.18453/rosdok_id00002503
1135503201
rda
DE-627
190724
1669963233
20251225T215051.0
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