%0 Book %T regenerative potential of the CD117+AT2R stimulated cell population in vitro and in vivo: = Das regenerative Potential der CD117+AT2R stimulierten Zellpopulation in vitro und in vivo %A Ludwig, Marion %D 2014 %G English %F 833973207 %O submitted by : Marion Ludwig %O Enth. 4 Beitr. aus versch. Ztschr %O Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2015 %X Regarding innovative therapeutical approaches for cardiac regeneration, we thoroughly investigated CD117+ and CD117+AT2R stimulated murine bone marrow stem cells. Electrophysiological measurements and in vitro results indicated the differentiation into an endothelial-like phenotype excluding a previously discussed development into cardiomyocytes. Cell implantation into infarcted murine heart provoked a significant improvement of cardiac function. AT2R triggered effects were not significantly different and should be analyzed in interplay with its opposing receptor AT1. %L 610 %9 theses %9 Text %9 Hochschulschrift %U http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2015-0146-3 %U http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2015-0146-3&pdf %U http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2015-0146-3