%0 Book
%T Synthesis of substituted 1-deazapurines via Pd/Cu catalysed C-H activation, substituted naphthyridines, quinoxalines, and trifluoromethyl-substituted arenes by Pd(0)-catalysed cross-coupling reactions
%A Ali, Iftikhar
%D 2011
%G English
%F 718223721
%O vorgelegt von Iftikhar Ali
%O Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2012
%X The Pd/Cu catalyzed reactions of 3H-imidazo[4,5-b]pyridines (1-deazapurines) via C-H bond activation provided arylated 1-deazapurines. The arylation took place at position 2 of the 1-deazapurines. Pd(0)-catalysed Suzuki-Miyaura cross coupling reactions of 5,7-dichloro-1,6-naphthyridine, 2,6-dichloroquinoxaline and 2,4-dichloro-1-(trifluoromethyl)benzene with different arylboronic acids afforded aryl-substituted naphthyridines, quinoxalines and trifluoromethyl-substituted di- and terphenyls with excellent site-selectivity. The first attack occurred at the more electronically deficient and sterically less hindered position.
%L 35.69
%9 theses
%9 Text
%9 Hochschulschrift
%U http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2012-0039-6
%U http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2012-0039-6&pdf
%U http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2012-0039-6