%0 Book
%T Palladium/di-1-adamantyl-n-butylphosphine-catalyzed carbonylation reactions
%A Brennführer, Anne
%D 2008
%G English
%F 604071264
%O Anne Brennführer
%O Enth. 6 Beitr. aus versch. Ztschr
%O Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2009
%X Within this thesis several homogeneous palladium-catalyzed carbonylation reactions in the presence of carbon monoxide were investigated. In the course of our studies, the superior performance of the catalyst system palladium acetate/di-1-adamantyl-n-butylphosphine (cataCXium® A) in comparison to established palladium catalysts was demonstrated for both reductive carbonylations and alkoxycarbonylations of aryl and vinyl bromides. Hence, a variety of (hetero)aromatic aldehydes and carboxylic acid derivatives (esters, amides, acids) were successfully synthesized, among them novel biologically interesting indolylmaleimides. Furthermore, an efficient method for the synthesis of non-steroidal anti-inflammatory drugs such as ketoprofen and suprofen was developed.
%L 540
%9 theses
%9 Text
%9 Hochschulschrift
%U http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0110-5
%U http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0110-5&pdf
%U http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2009-0110-5