%0 Book %T Cold plasma-mediated toxicity in cutaneous and ulcerating cancer tissues %A Saadati, Fariba %D 2024 %C Germany; Rostock %C Universität Rostock %G English %F 1984363999 %O vorgelegt von Fariba Saadati %O Enthält Zeitschriftenartikel %O GutachterInnen: Steffen Emmert (Klinik und Poliklinik für Dermatologie und Venerologie, Universitätsmedizin Rostock) ; Brigitte Vollmar (Rudolf-Zenker-Institut für Experimentelle Chirurgie, Universitätsmedizin Rostock) ; Martina Meinke (Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin) %O Dissertation Universität Rostock 2025 Kumulative Dissertation %X Breast cancer mortality and treatment side effects highlight the need for alternative or complementary therapies. Physical plasma has emerged as a promising anticancer approach. This thesis explores plasma’s effects on ulcerating breast cancer using 2D/3D in vitro models, in vivo xenografts, patient-derived tissues, and biopsies. Plasma consistently reduced tumor growth, induced programmed cell death, and modulated the tumor microenvironment. It also triggered systemic immune effects and showed no genotoxicity, supporting its safe and effective complementary therapy. %L 570 %9 theses %9 Text %9 Hochschulschrift %R 10.18453/rosdok_id00005802 %U https://purl.uni-rostock.de/rosdok/id00005802 %U https://doi.org/10.18453/rosdok_id00005802