%0 Book
%T Gender-specific impact of direct-coupled alternating electric fields on human chondrocytes
%A Song, Zezhong
%D 2024
%C Rostock
%C Universität Rostock
%G English
%F 1966684843
%O vorgelegt von Zezhong Song
%O GutachterInnen: Rainer Bader (Forschungslabor für Biomechanik und Implantattechnologie, Universität Rostock) ; Jessica Bertrand (Orthopädische Universitätsklinik mit Endoprothetikzentrum, Universitätsklinikum Magdeburg) ; Kirsten Peters (Center for Medical Research (ZEMFO), Institute of Cell Biology, Universität Rostock)
%O Dissertation Universität Rostock 2025
%X In cell-based therapy for cartilage repair, preventing fibrocartilage formation due to dedifferentiation is crucial. This study examined how alternating electric fields affect the redifferentiation of human chondrocytes from male and female donors. Stimulation at 15–20 V/m increased the Col2/Col1 ratio and promoted rounded morphology, indicating enhanced redifferentiation. Meanwhile, female chondrocytes showed more collagen 1 production and fibroblast-like shape. These results suggest male chondrocytes showed higher tendency towards redifferentiation in response to electrical stimulation.<eng>
%L 570
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00005205
%U https://purl.uni-rostock.de/rosdok/id00005205
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00005205-6
%U https://d-nb.info/1394543700/34
%U https://doi.org/10.18453/rosdok_id00005205