%0 Book
%T Function of energy-converting hydrogenases and transhydrogenase in the metabolism of the thermophilic acetogenic bacterium Thermoanaerobacter kivui
%A Baum, Christoph Ferdinand
%D 2024
%C Rostock
%C Universität Rostock
%G English
%F 1963653858
%O vorgelegt von Christoph Ferdinand Baum
%O GutachterInnen: Mirko Basen (Mikrobiologie, Institut für Biowissenschaften, Universität Rostock) ; Uwe Deppenmeier (Institut für Mikrobiologie und Biotechnologie, Universität Bonn)
%O Dissertation Universität Rostock 2025
%X Electron transfer between H₂, ferredoxin, NADH and NADPH is essential for the redox balance and energy metabolism in Thermoanaerobacter kivui. The hydrogenases Ech1 and Ech2 are important for energy conservation on H₂/CO₂ or CO. Deletion of Ech2 impaired growth on pyruvate and CO, but not on sugars. Ech1 could not be completely deleted, but downregulation led to similar effects. Deletion of the electron-bifurcating transhydrogenase NfnAB interfered with growth on all substrates, and mixotrophic growth studies with glucose showed H₂-induced growth inhibition.<eng>
%L 500
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00005153
%U https://purl.uni-rostock.de/rosdok/id00005153
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00005153-9
%U https://d-nb.info/1393157092/34
%U https://doi.org/10.18453/rosdok_id00005153