%0 Book %T Accessible tools for biomolecular data analysis using large-scale knowledge graphs %A Welzen, Matti van %D 2024 %C Rostock %C Universität Rostock %G English %F 1950629082 %O vorgelegt von Matti van Welzen %O GutachterInnen: Olaf Wolkenhauer (Universität Rostock) ; Dirk Repsilber (Örebro University) ; Anna Niarakis (Université Paul Sabatier) %O Dissertation Universität Rostock 2024 %X The interpretation of biomolecular data is often challenging due to the heterogeneity in the structural and functional organization of biological systems. In this thesis, I created knowledge graphs of disease processes, published as interactive Disease Maps, and developed new tools for their analysis. I present (i) the Atlas of Inflammation Resolution (AIR), (ii) the two-dimensional enrichment analysis (2DEA) as a novel network-based enrichment approach, (iii) the Sarcopenia Map linking gastrointestinal diseases and sarcopenia, and (iv) the MASLD Map investigating steatotic liver diseases. %L 004 %9 theses %9 Text %9 Hochschulschrift %R 10.18453/rosdok_id00005086 %U https://purl.uni-rostock.de/rosdok/id00005086 %U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00005086-2 %U https://d-nb.info/1388827212/34 %U https://doi.org/10.18453/rosdok_id00005086