%0 Book
%T Evaluating distress of animals in mouse models for liver fibrosis
%A Tang, Guanglin
%D 2023
%C Rostock
%C Universität Rostock
%G English
%F 1945998741
%O vorgelegt von Guanglin Tang
%O Enthält Zeitschriftenartikel
%O GutachterInnen: Dietmar Zechner (Universitätsmedizin Rostock) ; Robert Jaster (Universitätsmedizin Rostock) ; Kerstin Schwabe (Medizinische Hochschule Hannover)
%O Dissertation Universität Rostock 2024 Kumulative Dissertation
%X There are few studies that define which methods are appropriate to measure the severity of suffering in animals. In the first study, we showed that corticosterone elevation is an important parameter for the assessment of distress in mice. In the second study, we analyzed the diagnostic value of a distress score, burrowing activity and body weight change in animal models of liver fibrosis. In the third study, the power of single and multiple parameters to determine an early humane endpoint was analyzed.<eng>
%L 570
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00005031
%U https://purl.uni-rostock.de/rosdok/id00005031
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00005031-6
%U https://d-nb.info/1385075201/34
%U https://doi.org/10.18453/rosdok_id00005031