%0 Book
%T Establishing the greenhouse-production of FGF21-Transferrin in tobacco seeds and leaves for oral treatment of non-alcoholic steatosis hepatis NASH: = Etablierung der Gewächshausproduktion von FGF21-Transferrin in Tabaksamen und -blättern zur oralen Behandlung der nichtalkoholische Steatohepatitis NASH
%A Hou, Hsuan-Wu
%D 2024
%C Rostock
%C Universität Rostock
%G English
%F 1932007393
%O vorgelegt von Hsuan-Wu Hou
%O GutachterInnen: Henrik Nausch (Fraunhofer-Institut für Molekularbiologie und Angewandte Ökologie IME, Abt. Bioprozessentwicklung) ; Inge Broer (Universität Rostock, AUF, Agrobiotechnologie) ; Susanne Klaus (Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke (DIfE), Abt. Physiologie des Energiestoffwechsels) ; Rima Menassa (University of Western Ontario, Biology Department / London Research and Development Centre, Agriculture and Agri-Food Canada)
%O Dissertation Universität Rostock 2024
%X Thesis focuses on the production of a variant of the human fibroblast growth factor (FGF21) in plants. This factor is supposed to support the liver function, but has a negative impact on other organs. Hence it has to be directed directly to the liver and should be unstable to avoid its presence in other organs. An oral intake would be preferred. Plants provide an excellent platform for the production of orally applied pharmaceuticals since the cell wall protects the substance from premature degradation in the gastric system.<eng>
%L 580
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00004889
%U https://purl.uni-rostock.de/rosdok/id00004889
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004889-6
%U https://d-nb.info/1373150777/34
%U https://doi.org/10.18453/rosdok_id00004889