%0 Book
%T Evaluating in vitro toxicity of flavors in alternative nicotine delivery systems utilizing different in vitro testing strategies
%A Rinaldi, Selina
%D 2025
%C Rostock
%C Universität Rostock
%G English
%F 1931303371
%O vorgelegt von Selina Rinaldi
%O Der Volltext der Zeitschriftenartikel ist nur in der Druckausgabe vorhanden
%O GutachterInnen: Ralf Zimmermann (University of Rostock, Institute of Chemistry) ; Tanja Schwerdtle (Max Rubner-Institut and University of Potsdam, Institute of Nutritional Science, Department of Food Chemistry)
%O Dissertation Universität Rostock 2025 Kumulative Dissertation
%X The respiratory and local health effects of flavors in alternative nicotine delivery systems (ANDS) are not well understood. This dissertation aimed to develop an in vitro risk assessment strategy for ANDS flavors and identify oral nicotine pouch (ONP) ingredients. Further, the impinger method was optimized for collecting flavored aerosols. Based on the results, a tiered testing approach is advised using submerged and Air-Liquid Interface cell models. Further, standardized testing guidelines for flavoring compounds in emerging ANDS are needed for comprehensive safety assessments.<eng>
%L 500
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00004874
%U https://purl.uni-rostock.de/rosdok/id00004874
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004874-8
%U https://d-nb.info/1372071903/34
%U https://doi.org/10.18453/rosdok_id00004874