%0 Book
%T Characterization and comparison of the angiogenic and cardio-regenerative potential of mesenchymal CD271+ and hematopoietic CD133+ bone marrow stem cells by means of in vitro and in vivo angiogenesis models
%A Sasse, Sarah Hélène
%D 2020
%C Rostock
%C Universität Rostock
%G English
%F 1926637526
%O vorgelegt von Sarah Hélène Sasse
%O GutachterInnen: Gustav Steinhoff (Universitätsklinik Rostock) ; Christian Junghanß (Universitätsklinik Rostock) ; Christof Stamm (Deutsches Herzzentrum Charité)
%O Dissertation Universität Rostock 2024
%X This study intends to examine the therapeutic potential of mesenchymal CD271+ stem cells in comparison to hematopoietic CD133+ cells with regard to their application in myocardial infarction. At his, in vitro proliferation assays showed that the application of CD271+ stem cells results in improved angiogenic potential and the combination of CD133+ and CD271+ cells seems to be the most effective approach. Furthermore, an in vivo analysis has been performed in a mouse-model with ligation of the left anterior descendent artery.<eng>
%L 500
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00004808
%U https://purl.uni-rostock.de/rosdok/id00004808
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004808-9
%U https://d-nb.info/136824288X/34
%U https://doi.org/10.18453/rosdok_id00004808