%0 Book %T comprehensive chemical characterization of the active pharmaceutical ingredients in bituminosulfonates: a case study for the elucidation of complex drugs %A Schwalb, Lukas Felix %D 2024 %C Rostock %C Universität Rostock %G English %F 1923793500 %O vorgelegt von Lukas Felix Schwalb %O Der Volltext der Zeitschriftenartikel ist nur in der Druckausgabe vorhanden %O GutachterInnen: Ralf Zimmermann (Universität Rostock) ; Erwin Rosenberg (TU Wien) %O Dissertation Universität Rostock 2024 Kumulative Dissertation %X The comprehensive chemical description of active pharmaceutical ingredients (APIs) of complex drugs is an analytical challenge. This also applies to bituminosulfonates. This study addresses the in-depth chemical description of the APIs and their characteristic manufacturing process via applying and adapting comprehensive two-dimensional gas chromatography coupled with high-resolution mass spectrometry (GCxGC HR-MS). As a result, it describes comprehensively and in detail the chemical identity of the bituminosulfonates and their manufacturing process at the molecular level. %L 500 %9 theses %9 Text %9 Hochschulschrift %R 10.18453/rosdok_id00004765 %U https://purl.uni-rostock.de/rosdok/id00004765 %U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004765-1 %U https://d-nb.info/1365412342/34 %U https://doi.org/10.18453/rosdok_id00004765