%0 Book
%T Strategies to control mouse populations: production of species-specific contraceptive peptides in plants as oral vaccine = Strategien zur Kontrolle von Mäusepopulationen : Produktion artspezifischer kontrazeptiver Peptide in Pflanzen als oraler Impfstoff
%A Ghasemian, Khadijeh
%D 2023
%C Rostock
%C Universität Rostock
%G English
%F 190217822X
%O submitted by Khadijeh Ghasemian
%O Enthält Zeitschriftenartikel
%O GutachterInnen: Inge Broer (AUF, Agrobiotechnologie) ; Julian Ma (Georges University of London, Institute for Infection and Immunity) ; Dirk Prüfer (Westfälische Wilhelms-Universität Münster, Institut für Biologie und Biotechnologie der Pflanzen) ; Eva Stöger (Universität für Bodenkultur Wien (BOKU), Department für Angewandte Genetik und Zellbiologie, Institut für Pflanzenbiotechnologie und Zellbiologie)
%O Dissertation Universität Rostock 2023 Kumulative Dissertation
%X The aim of the study was to develop strategies to produce an oral contraceptive vaccine for mice in plants, in order to reduce the mouse population. The results showed that mouse-specific contraceptive peptides were successfully produced in plants. All peptides induced IgG antibodies in subcutaneously vaccinated mice. Moreover, oral delivery of the leaves expressing a fusion protein elicited systemic and mucosal cross-reactive antibodies. Observations suggest that plant-produced contraceptives have the potential to be used in the development of feeding baits to reduce the fertility of mice.<eng>
%L 580
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00004672
%U https://purl.uni-rostock.de/rosdok/id00004672
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004672-2
%U https://d-nb.info/1342194268/34
%U https://doi.org/10.18453/rosdok_id00004672