%0 Book
%T Cellular and molecular toxicity of atmospherically aged anthropogenic and biogenic aerosols
%A Offer, Svenja Hannah
%D 2023
%C Germany; Rostock
%C Universität Rostock
%G English
%F 1857865693
%O vorgelegt von Svenja Hannah Offer
%O Enthält Zeitschriftenartikel
%O GutachterInnen: Ralf Zimmermann (Institut für Chemie, Universität Rostock) ; Barbara Rothen-Rutishauser (Adolphe Merkle Institut, Universität Fribourg, Schweiz)
%O Dissertation Universität Rostock 2023 Kumulative Dissertation
%X This dissertation addresses the question about the toxicological impacts of atmospherically aged biogenic and anthropogenic emissions. In simulation experiments, an anthropogenic (naphthalene) or biogenic (β-pinene) VOC precursor was aged together with a primary aerosol and comprehensively physical and chemical characterized. Using different in vitro airway model systems [BEAS-2B, A549 and a coculture of A549/EA.hy926] in an automated air-liquid interface exposure system, the cellular effects triggered by the aerosols were tested by evaluating the genomic, metabolomic and functional changes.<eng>
%L 500
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00004409
%U http://purl.uni-rostock.de/rosdok/id00004409
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004409-8
%U https://d-nb.info/130101673X/34
%U https://doi.org/10.18453/rosdok_id00004409