%0 Book %T Synthesis of small molecules for skin cancer treatment with plasma and non-plasma application %A Frey, Anna Katharina %D 2022 %C Rostock %C Universität Rostock %G English %F 1823889271 %O vorgelegt von Anna Katharina Frey %O GutachterInnen: Peter Langer (Insitut für Chemie, Universität Rostock) ; Burkhard Hinz (Institut für Pharmakologie und Toxikologie, Universität Rostock) ; Jens Christoffers (Institut für Chemie, Carl von Ossietzky Universität Oldenburg) %O Dissertation Universität Rostock 2022 %X This dissertation deals with the synthesis of small molecules for use in skin cancers with possible plasma application. First, N-glycosylated oxindoles and N-glycosylated isatins bearing electron-withdrawing substituents were synthesized. Furthermore, highly functionalized synthetic building blocks were synthesized in regio- and chemo selective palladium-catalyzed coupling reactions with various boronic acids and alkynes, which then reacted to form heterocycles by acid-mediated cycloisomerization or alkyne-carbonyl metathesis. %L 500 %9 theses %9 Text %9 Hochschulschrift %R 10.18453/rosdok_id00004037 %U http://purl.uni-rostock.de/rosdok/id00004037 %U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004037-0 %U https://d-nb.info/1293539244/34 %U https://doi.org/10.18453/rosdok_id00004037