%0 Book
%T Identification of the microsatellite stability status and inhibitor of NF-kappa-B expression levels as biomarkers to predict sensitivity to pharmaceutical curcumin in colorectal cancer cells
%A Lu, Lili
%D 2021
%C Rostock
%C Universität Rostock
%G English
%F 177105252X
%O vorgelegt von Lili Lu
%O GutachterInnen: Michael Linnebacher (Molekulare Onkologie und Immuntherapie, Allgemeine Chirurgie, Universitätsmedizin Rostock) ; Robert Ramer (Institut für Pharmakologie und Toxikologie, Universitätsmedizin Rostock) ; Oliver H. Krämer (Institut für Toxikologie, Universitätsmedizin der Johannes-Gutenberg-Universität Mainz)
%O Dissertation Universität Rostock 2021
%X The present study aimed at 1) testing the sensitivity of CRC cell lines with defined molecular alterations to curcumin; 2) mechanistically analyzing sensitive CRC cell lines in order to identify the mode-of-action; 3) identifying biomarkers associated with curcumin sensitivity; 4) establishing a predictive model using biomarkers to predict the sensitivity of additional CRC cell line to curcumin.<eng>
%L 500
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00003164
%U http://purl.uni-rostock.de/rosdok/id00003164
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00003164-0
%U https://d-nb.info/1293534625/34
%U https://doi.org/10.18453/rosdok_id00003164