%0 Book
%T Antiarrhythmic effect of human bone marrow-dereived CD271+ mesenchymal stem cells tested in vivo using a new infarction-re-infarction mouse model
%A Sadraddin, Haval Lutfalla
%D 2019
%C Rostock
%C Universität Rostock
%G English
%F 175043959X
%O vorgelegt von Haval Lutfalla Sadraddin
%O GutachterInnen: Christof Stamm (Deutsches Herzzentrum Berlin, BIH Center for Regenerative Therapies, Charite Universitätsmedizin) ; Gustav Steinhoff (Universitätsmedizin Rostock, Klinik und Poliklinik für Herzchirurgie) ; Brigitte Vollmar (Universitätsmedizin Rostock, Rudolf-Zenker-Institut für Experimentelle Chirurgie)
%O Dissertation Universität Rostock 2021
%X This experiment showed the safety and antiarrhythmic effect of human bone marrow-derived CD271+ MSC. This was performed in immune deficient mice (Rag2-/-γc-/--mice) with electrocardiogram monitoring through Implantation of telemtry system. The induction of ventricular arrhythmias has been achieved via a permanent re-infarction through left anterior descending artery (LAD) ligation one week after a 30-minute ischemia-reperfusion. The time between 2 infarctions gave the stem cells the required period to entgraft themselves after their intramyocardial injection with the first infarction.<eng>
%L 610
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00002970
%U http://purl.uni-rostock.de/rosdok/id00002970
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002970-5
%U https://d-nb.info/129366278X/34
%U https://doi.org/10.18453/rosdok_id00002970