%0 Book
%T In-vitro-Analyse zur Wirkung ionisierender Strahlung auf Adipose-derived stem cells der weiblichen Brust
%A Schröder, Annemarie
%D 2020
%C Rostock
%C Universität Rostock
%G German
%F 1748145525
%O vorgelegt von Annemarie Schröder
%O Enthält Zeitschriftenartikel
%O Innerhalb dieser Arbeit wurden Bestandteile in folgenden Publikationen veröffentlicht: .g Baaße, A.; Juerß, D.; Reape, E.; Manda, K.; Hildebrandt, G. . Promoting effects of adipose-derived stem cells on breast cancer cells are reversed by radiation therapy. Cytotechnology 2018, 70, 701–711, . https://doi.org/10.1007/s10616-017-0172-6. Baaße, A.; Machoy, F.; Juerß, D.; Baake, J.; Stang, F.; Reimer, T.; Krapohl, B.; Hildebrandt, G. Radiation Sensitivity of Adipose-Derived Stem Cells Isolated from Breast Tissue. Int. J. Mol. Sci. 2018, 19, 1988, doi:10.3390/ijms19071988. Schröder, A.; Kriesen, S.; Hildebrandt, G.; Manda, K. First Insights into the Effect of Low-Dose X-Ray Irradiation in Adipose-Derived Stem Cells. Int. J. Mol. Sci. 2019, 20, 6075
%O GutachterInnen: Reinhard Schröder (Universität Rostock, Institut für Biowissenschaften, Abt. Genetik) ; Guido Hildebrandt (Universitätsmedizin Rostock, Klinik und Poliklinik für Strahlentherapie) ; Fritz-Olaf Lehmann (Universität Rostock, Institut für Biowissenschaften Abt. Tierphysiologie)
%O Dissertation Universität Rostock 2021 Kumulative Dissertation
%X Within breast tissue, adipose-derived stem cells (ADSCs) are responsible for maintaining cellular homeostasis. However, this potential can also contributed to the undesirable effect of tumor promotion. Therefore, this work deals with the effect of ionizing radiation on these interactions. In summary, the promoting effects of ADSCs on MCF-7 breast cancer cells were neutralized or reversed by a radiation treatment. Furthermore, ADSCs exhibit a medium radiation sensitivity associated with a functional DNA repair system.<eng>
%L 570
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00002925
%U http://purl.uni-rostock.de/rosdok/id00002925
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002925-6
%U https://d-nb.info/1293662585/34
%U https://doi.org/10.18453/rosdok_id00002925