%0 Book
%T Customized workflow development and omics data integration concepts in systems medicine
%A Wolfien, Markus
%D 2020
%C Rostock
%C Universität Rostock
%G English
%F 1743350384
%O vorgelegt von Markus Wolfien
%O GutachterInnen: Olaf Wolkenhauer (Universität Rostock) ; David Ellinghaus (Christian-Albrechts-Universität zu Kiel) ; Stefan Simm (Universitätsmedizin Greifswald)
%O Enthält Zeitschriftenbeiträge
%O Dissertation Universität Rostock 2020
%X The ever-increasing amount and diversity of biological and medical data is a major challenge in computational analyses. Computational methods have to be combined into analysis workflows for seamless, swift, and transparent computation. In this work, numerous workflows were developed for the general processing of bulk RNA sequencing (RNA-Seq), single-cell sequencing experiments, and non-coding RNA identification. Mathematical concepts of machine learning and univariate meta-analyses were successfully implemented to independently investigate the role of cell therapies in cardiac regeneration.<eng>
%L 004
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00002868
%U http://purl.uni-rostock.de/rosdok/id00002868
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002868-5
%U https://d-nb.info/129366183X/34
%U https://doi.org/10.18453/rosdok_id00002868