%0 Book %T Synthesis of functionalized pyridines and quinolines by palladium-catalyzed cross-coupling reactions %A Perdomo Rivera, Rodisnel %D 2018 %C Rostock %C Universität Rostock %G English %F 167123913X %O vorgelegt von Rodisnel Perdomo Rivera %O GutachterInnen: Peter Langer (Universität Rostock, Institut für Chemie) ; Bernd Schmidt (Universität Potsdam, Institut für Chemie) %O Dissertation Universität Rostock 2018 %X This thesis deals with the functionalization of pentahalogenated pyridines and dihalogenated quinolines through palladium catalyzed cross coupling reactions. This includes the chemo-selective arylation and alkynylation of 4-bromo-2,3,5-trichloro-6-iodopyridine using Suzuki and Sonogashira reactions. The chemo-selective arylation of 4,6-dihalogenated-2-(trifluoromethyl)quinoline by Suzuki reaction was studied. Besides, the synthesis of indolo [2,3-c]quinolines was studied by sequential chemo-selective Suzuki reaction followed by double C-N coupling starting from 3-bromo-4-iodoquinoline. %L 540 %9 theses %9 Text %9 Hochschulschrift %R 10.18453/rosdok_id00002513 %U http://purl.uni-rostock.de/rosdok/id00002513 %U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002513-0 %U https://d-nb.info/1293657328/34 %U https://doi.org/10.18453/rosdok_id00002513