%0 Book
%T Two Zona Pellucida vaccines expressed in different plant expression systems for spaying mammals
%A Masloboy, Axel
%D 2018
%C Rostock
%C Universität Rostock
%G English
%F 1662422075
%O vorgelegt von Axel Masloboy
%O GutachterInnen: Inge Broer (Universität Rostock, Agrar- und Umweltwissenschaftliche Fakultät, Agrobiotechnologie) ; Ann Depicker (Universiteit Gent, VIB)
%O Dissertation Universität Rostock 2018
%X This is a concept study of designing two contraceptive vaccines, expressing them in different plant expression systems und testing their efficacy. As antigens fertilization-relevant Zona Pellucida proteins were used. Stable transformed pea seeds, tobacco seeds, tobacco leaves and carrot cells show vaccine accumulation. A transient expression system was used for producing and characterizing the vaccines. The vaccines elicited a strong immune response, which reduced offspring of BALB/c mice up to 52 %.<eng>
%L 570
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00002426
%U http://purl.uni-rostock.de/rosdok/id00002426
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002426-0
%U https://d-nb.info/1293533912/34
%U https://doi.org/10.18453/rosdok_id00002426