%0 Book
%T impact of bacteria and their cell wall components LPS and LTA on proliferation, differentiation and migration of human adipose-derived mesenchymal stem cells in vitro
%A Herzmann, Nicole
%D 2017
%C Rostock
%C Universität Rostock
%G English
%F 1025278135
%O submitted by Nicole Herzmann
%O Enthält Beiträge aus verschiedenen Zeitschriften
%O Dissertation Universität Rostock 2018
%X The aim of the studies was to analyze the influence of Gram-negative and -positive wound infection relevant bacteria and their cell wall components LPS and LTA on cellular processes (e.g. proliferation, osteogenic and adipogenic differentiation, NF-kappaB signaling, migration and chemotaxis) of adMCS. We could show that, the LPS-induced increase in proliferation and osteogenic differentiation of adMSC could be abolished by competitive inhibition of TLR4. The data strengthen the evidence for a role of TLR4 in the regulation of proliferation and differentiation of adMSC.<eng>
%L 610
%9 theses
%9 Text
%9 Hochschulschrift
%R 10.18453/rosdok_id00002103
%U http://rosdok.uni-rostock.de/resolve/id/rosdok_disshab_0000001925
%U https://nbn-resolving.org/urn:nbn:de:gbv:28-diss2018-0097-1
%U https://d-nb.info/1293652857/34
%U https://doi.org/10.18453/rosdok_id00002103