Oral bacteria, stem cells and neutrophils in vitro: a model for periodontal infection Hieke, Cathleen , 1989- (VerfasserIn) Kreikemeyer, Bernd , 1966- (GutachterIn) Bahl, Hubert , 1955- (GutachterIn) Universität Rostock (Grad-verleihende Institution) Universität Rostock Mathematisch-Naturwissenschaftliche Fakultät (Grad-verleihende Institution) Text theses Text Hochschulschrift 2017 [2017] eng electronic resourceremoteComputermedienOnline-Ressource1 Online-Ressource Periodontitis is a chronic inflammatory disease induced by bacteria from oral biofilms. Bacteria interact with host cells and can subsequently provoke activation of polymorphonuclear neutrophils (PMNs). In this study, an in vitro model was applied to investigate interactions between periodontal pathogens, i.e., P. intermedia, T. forsythia and P. gingivalis, human dental stem cells (hDFSCs) and PMNs. HDFSCs modulate immune activity of PMNs after infection with oral bacteria implying general suitability of hDFSCs in tissue regeneration strategies after tissue damage in periodontal infections.<eng> vorgelegt von Cathleen Hieke aus Rostock Dissertation Universität Rostock 2017 570 42.30 http://rosdok.uni-rostock.de/resolve/urn/urn:nbn:de:gbv:28-diss2017-0105-5 Oral bacteria, stem cells and neutrophils in vitro--(DE-627)894106899 urn:nbn:de:gbv:28-diss2017-0105-5 oclc: 994634035 ppn: (DE-627)894195999