Caveolae-mediated phagocytosis of biomaterial surface structures by human osteoblasts Mörke, Caroline , 1989- (VerfasserIn) Nebe, Barbara , 1958- (GutachterIn) Kuznetsov, Sergei (GutachterIn) Boer, Jan de (GutachterIn) Universität Rostock (Grad-verleihende Institution) Universität Rostock Mathematisch-Naturwissenschaftliche Fakultät (Grad verleihende Institution) Text theses Text Hochschulschrift 2016 2016 eng electronic resourceremoteComputermedienOnline-Ressource1 Online-Ressource Cells are sensitive to their underlying topography, which evoke large ranges of cell responses. The work describes an attempted caveolae-mediated phagocytosis of the surface-fixed micro-pillars by human MG-63 osteoblastic cells. This attempt to phagocytize the elevations of the Ti surface results in higher energy requirements for the cells and finally to impaired osteoblast function. Similar cell responses were observed for the osteoblasts treated with micro-particles as phagocytosis trigger and osteoblasts growing on stochastic rough Ti surfaces, commercially used as implant surfaces.<eng> vorgelegt von Caroline Mörke Dissertation Universität Rostock 2016 570 42.99 http://rosdok.uni-rostock.de/resolve/urn/urn:nbn:de:gbv:28-diss2016-0099-5 Caveolae-mediated phagocytosis of biomaterial surface structures by human osteoblasts--(DE-627)864742592 urn:nbn:de:gbv:28-diss2016-0099-5 oclc: 956767702 ppn: (DE-627)865832447