Routes to polysubstituted and condensed pyridines and diazines - utilization of 1,3-bielectrophiles and transition metal-based catalysis in ring synthesis/modification Ostrovskyi, Dmytro , 1986- Text theses Text Hochschulschrift 2012 2012 eng electronic resourceremoteComputermedienOnline-Ressourcetext/htmlapplication/pdfOnline-Ressource graph. Darst. The present work aimed to study the potential of well-known synthetic strategies for the synthesis of imidazo[4,5-b]pyridine-derived (or 1-desazapurine-derived), purine-derived and benzimidazole-derived moieties and their modifications. This includes [3+3] cyclocondensations, inverse electron-demand Diels-Alder reaction, intramolecular palladium-catalyzed arylation. In addition, unprecedented method of synthesis of 4-trifluoromethylpyridines was developed, including scope limitation and theoretical mechanistic studies with DFT methods. vorgelegt von Dmytro Ostrovskyi Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2012 Organische Chemie http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0008-6 http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2013-0008-6&pdf http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2013-0008-6 Routes to polysubstituted and condensed pyridines and diazines - utilization of 1,3-bielectrophiles and transition metal-based catalysis in ring synthesis/modification--(DE-627)733544312 urn:nbn:de:gbv:28-diss2013-0008-6 oclc: 934946154 ppn: (DE-627)734092741