Polymervermittelter Gentransfer für die Therapie mit adulten Stammzellen Polymer mediated gene delivery for adult stem cell therapy Polymer mediated gene delivery for adult stem cell therapy Wang, Weiwei , 1979- Text theses Text Hochschulschrift 2010 2010 eng electronic resourceremoteComputermedienOnline-Ressourcetext/htmlapplication/pdfOnline-Ressource Ill., graph. Darst. Polymer mediated gene delivery was studied and utilized in adult stem cell therapy. The gene expression of human mesenchymal stem cells (MSCs) could be significantly enhanced by polyethylenimine (PEI) mediated gene delivery. The tumor cell growth could be effectively inhibited both in vitro and in vivo by delivering antisense oligonucleotide with non-viral method. Furthermore, gene activated substrate (GAS) prepared in this study could allow localized gene delivery, sustained gene release, high transfection efficiency, low cytotoxicity and high potential for stem cell recruitment. vorgelegt von Weiwei Wang Enth. 5 Beitr. aus versch. Ztschr Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2011 Online-Ausg.: [Online-Ausg.] Reproduktion 2011 [Online-Ausg.] Online-Ausg.: |2011|||||||||| Langzeitarchivierung gewährleistet pdager 610 610 42.13 44.09 http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2011-0070-9 http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2011-0070-9&pdf http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2011-0070-9 http://d-nb.info/1014239990/34 http://rosdok.uni-rostock.de/file/rosdok_derivate_000000004608/Dissertation_Wang_2011.pdf Polymervermittelter Gentransfer für die Therapie mit adulten Stammzellen--(DE-627)657062545 urn:nbn:de:gbv:28-diss2011-0070-9 oclc: 752075133 ppn: (DE-627)658204726