Stem cells therapy after myocardial infarction: direct application or drug-mediated recruitment? Stammzell-Therapie nach Myokardinfarkt Stammzell-Therapie nach Myokardinfarkt Furlani, Dario , 1976- Text theses Text Hochschulschrift 2009 2009 eng electronic resourceremoteComputermedienOnline-Ressourcetext/htmlapplication/pdfpdfOnline-Ressource Ill., graph. Darst. Heart failure after myocardial infarction is the first cause of death in west countries. Stem cells could ameliorate this process by inducing neoangiogenesis and/or cardiac myocytes regeneration. This thesis focused on two crucial topics: drug mediated stem cell recruitment and safety issues related to stem cell transplantation. The effects of stem cells mobilization and cardiac recruitment induced by Erythropoietin through the activation of SDF-1/CXCR4 axis were examined. The safety of mesenchymal stem cells intraarterial transplantation and ex-vivo expansion were investigated. submitted by Dario Furlani Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2010 Online-Ausg. Reproduktion [2010] Online-Ausg |2010|||||||||| 610 610 44.85 http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2010-0045-6 http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2010-0045-6&pdf http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2010-0045-6 http://rosdok.uni-rostock.de/metadata/rosdok_disshab_000000000412 http://d-nb.info/1003037283/34 http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2010-0045-6 Stem cells therapy after myocardial infarction--(DE-627)621449253 urn:nbn:de:gbv:28-diss2010-0045-6 oclc: 650701513 ppn: (DE-627)622388339