Towards electrochemical PCR-chips - contributions to couple enzymatic amplification and electrochemical detection of DNA Duwensee, Heiko , 1980- Text theses Text Hochschulschrift 2009 2009 eng electronic resourceremoteComputermedienOnline-Ressourcetext/htmlapplication/pdfOnline-Ressource Ill., graph. Darst. In this work the electrochemical DNA detection at heated electrodes as one alternative to the classical methods for the detection of DNA is presented. At elevated temperature an increase in sensitivity and selectivity as well as the minimization of electrode fouling could be observed. Surface modifications in the nano scale could further more improve the sensitivity. Procedures to detect genetically modified maize (MON 810) and PCR products were developed. The combination of DNA amplification and electrochemical detection was demonstrated. vorgelegt von Heiko Duwensee Enth. 11 Beitr. aus versch. Ztschr Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2009 570 http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0121-6 http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2009-0121-6&pdf http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2009-0121-6 Towards electrochemical PCR-chips - contributions to couple enzymatic amplification and electrochemical detection of DNA--(DE-627)604526814 urn:nbn:de:gbv:28-diss2009-0121-6 oclc: 455628030 ppn: (DE-627)604910150