Distress analysis of mice used for translational research: reflection of a surgeon on animal welfare Xie, Wentao , 1984- (VerfasserIn) Zechner, Dietmar , 1969- (AkademischeR BetreuerIn) Murua Escobar, Hugo Istvan , 1973- (AkademischeR BetreuerIn) Lindauer, Ute (AkademischeR BetreuerIn) Universität Rostock (Grad-verleihende Institution) Universitätsmedizin Rostock (Grad-verleihende Institution) Text theses Text Hochschulschrift 2022 2022 eng electronic resourceremoteComputermedienOnline-Ressourceapplication/pdf1 Online-Ressource (verschiedene Seitenzählungen) Illustrationen, Diagramme The assessment and improvement of animal welfare is not only an ethical requirement, but also a guarantee of efficient and high quality translational research. In recent years, sophisticated animal models were created to study human diseases. However, the assessment of distress in these animal models is scarce. In order to provide a solid basis for optimizing animal welfare in future studies, body weight, burrowing, nesting activity, faecal corticosterone metabolites (FCMs), and distress scores were analyzed in several animal models.<eng> Open Access Namensnennung 4.0 International vorgelegt von Wentao Xie Enthält Zeitschriftenartikel Publications: Wentao Xie, Marcel Kordt, Rupert Palme, Eberhard Grambow, Brigitte Vollmar, Dietmar Zechner. Diagnostic Ability of Methods Depicting Distress of Tumor-Bearing Mice. Animals. 2021;1:2155. Wentao Xie, Rupert Palme, Clemens Schafmayer, Dietmar Zechner, Brigitte Vollmar, Eberhard Grambow. Distress Analysis of Mice with Cervical Arteriovenous Fistulas. Animals. 2021;11:3051. WentaoXie, Matthias Lorenz, Friederike Poosch, Rupert Palme, Dietmar Zechner, Brigitte Vollmar, Eberhard Grambow, Daniel Strüder. 3D-printed lightweight dorsal skin fold chambers from PEEK reduce chamber-related animal distress. Sci Rep. 2022;12:11599 GutachterInnen: Dietmar Zechner (Universitätsmedizin Rostock) ; Hugo Murua Escobar (Universitätsmedizin Rostock) ; Ute Lindauer (RWTH Aachen) Dissertation Universität Rostock 2023 Kumulative Dissertation 570 610 616.994 610 YI 7412 44.81 44.03 44.65 http://purl.uni-rostock.de/rosdok/id00004344 https://doi.org/10.18453/rosdok_id00004344 https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004344-6 https://d-nb.info/1297583035/34 Distress analysis of mice used for translational research--(DE-627)1851812180 urn:nbn:de:gbv:28-rosdok_id00004344-6 doi: 10.18453/rosdok_id00004344 oclc: 1389341754 ppn: (DE-627)1851811249