Hydrogen / deuterium exchange reactions: small variations for heavy changes Bourriquen, Florian Marwan , 1995- (VerfasserIn) Beller, Matthias , 1962- (AkademischeR BetreuerIn) Gemmeren, Manuel van , 1985- (AkademischeR BetreuerIn) Universität Rostock (Grad-verleihende Institution) Universität Rostock Mathematisch-Naturwissenschaftliche Fakultät (Grad-verleihende Institution) Text theses Text Hochschulschrift 2022 12.12.2022 eng ger electronic resourceremoteComputermedienOnline-Ressource1 Online-Ressource (X, 78 Seiten) Illustrationen, Diagramme This dissertation reports the development of new catalytic methodologies for deuterium incorporation into organic molecules. In a first part, the use of a simple Lewis acid is reported for the isotopic labelling of electron-rich (hetero)arenes. Next, two heterogeneous catalysts are presented for the labelling of comparable compounds: a first-generation iron-based system and a follow-up work using manganese. Both materials are easily prepared and fully characterised. Additionally, investigations were performed to gain insight on the mechanisms.<eng> Open Access Urheberrechtsschutz 1.0 vorgelegt von Florian Bourriquen Year of oral defence: 2023 Enthält Zeitschriftenartikel GutachterInnen: Matthias Beller (Leibniz-Institut für Katalyse e.V.) ; Manuel van Gemmeren (Christian-Albrechts-Universität zu Kiel) Dissertation Universität Rostock 2023 Kumulative Dissertation 540 541 540 VK 5557 35.17 http://purl.uni-rostock.de/rosdok/id00004295 https://doi.org/10.18453/rosdok_id00004295 https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004295-8 https://d-nb.info/1292078758/34 Hydrogen / deuterium exchange reactions--(DE-627)1845698053 urn:nbn:de:gbv:28-rosdok_id00004295-8 doi: 10.18453/rosdok_id00004295 oclc: 1379272367 ppn: (DE-627)1845697952