Astrocytic expression of aldehyde dehydrogenase family 1 member L1 Liu, Feifei , 1985- (VerfasserIn) Kipp, Markus , 1978- (AkademischeR BetreuerIn) Büttner, Andreas , 1961- (AkademischeR BetreuerIn) Clamer, Tim (AkademischeR BetreuerIn) Universität Rostock (Grad-verleihende Institution) Universitätsmedizin Rostock (Grad-verleihende Institution) Text theses Text Hochschulschrift 2022 2022 eng electronic resourceremoteComputermedienOnline-Ressource1 Online-Ressource (81 Seiten) Illustrationen, Diagramme Astrocytes are the most numerous cell population of glia in the central nervous system. This study mainly focused on the astrocytic expression of aldehyde dehydrogenase family 1 member L1 (ALDH1L1) under physiological and pathological conditions. Brain sections from 3 control humans, 3 multiple sclerosis patients, 5 control mice, and 15 mice intoxicated with cuprizone were applied. Immunohistochemical and immunofluorescent staining was performed to analyze the expression of ALDH1L1 by astrocytes. The results indicated a dynamic regulation of ALDH1L1 in both the healthy and diseased CNS.<eng> Open Access Urheberrechtsschutz 1.0 vorgelegt von Feifei Liu GutachterInnen: Markus Kipp (Institut für Neuroanatomie, Universitätsmedizin Rostock) ; Andreas Büttner (Institut für Rechtsmedizin, Universitätsmedizin Rostock) ; Tim Clamer (Institut für Neuroanatomie, Universitätsklinikum Aachen) Dissertation Universität Rostock 2023 610 616.8 610 44.90 44.34 42.15 http://purl.uni-rostock.de/rosdok/id00004246 https://doi.org/10.18453/rosdok_id00004246 https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004246-3 https://d-nb.info/1292079088/34 Astrocytic expression of aldehyde dehydrogenase family 1 member L1--(DE-627)1843343002 urn:nbn:de:gbv:28-rosdok_id00004246-3 doi: 10.18453/rosdok_id00004246 oclc: 1376988237 ppn: (DE-627)1843341905