Molecular recognition studies by nanoESI mass spectrometry Danquah, Bright D. , 1987- (VerfasserIn) Glocker, Michael , 1960- (AkademischeR BetreuerIn) Gerner, Christopher (AkademischeR BetreuerIn) Füllen, Georg , 1967- (AkademischeR BetreuerIn) Universität Rostock (Grad-verleihende Institution) Universitätsmedizin Rostock (Grad-verleihende Institution) Text theses Text Hochschulschrift 2019 2019 eng electronic resourceremoteComputermedienOnline-Ressource1 Online-Ressource Analytical methods that characterize antibody-antigen interactions are certainly worth developing as they illuminate our understanding of molecular mechanisms of certain disease processes, and ultimately provide opportunities to improve existing treatment and management of such diseases by designing novel therapeutics. In this thesis, the challenges associated with the existing methods have been surpassed by developing simple but accurate nanoESI mass spectrometry methods which can be used to characterize antibody specificities as well as estimation of their binding affinities.<eng> vorgelegt von Bright Djan Danquah Enthält Zeitschriftenartikel GutachterInnen: Michael O. Glocker (Universität Rostock, Proteom Zentrum Rostock) ; Christopher Gerner (Universität Wien, Institut für Analytische Chemie) ; Georg Füllen (Universität Rostock, Institut für Biostatistik und Informatik in Medizin und Alternsforschung) Dissertation Universität Rostock 2019 500 610 616.079 610 WX 2201 42.03 44.45 http://purl.uni-rostock.de/rosdok/id00002661 https://doi.org/10.18453/rosdok_id00002661 https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002661-6 https://d-nb.info/1293659509/34 Molecular recognition studies by nanoESI mass spectrometry--(DE-627)1696997895 urn:nbn:de:gbv:28-rosdok_id00002661-6 doi: 10.18453/rosdok_id00002661 oclc: 1152564539 ppn: (DE-627)1696923514