Computational investigation of the response of osteoblasts in interaction with substrate under effects of electric field exposure Truong, Thanh Duy , 1987- (VerfasserIn) Rienen, Ursula van , 1957- (AkademischeR BetreuerIn) Nebe, Barbara , 1958- (AkademischeR BetreuerIn) García Aznar, José Manuel (AkademischeR BetreuerIn) Universität Rostock (Grad-verleihende Institution) Universität Rostock Fakultät für Informatik und Elektrotechnik (Grad-verleihende Institution) Text theses Text Hochschulschrift 2018 2018 eng electronic resourceremoteComputermedienOnline-Ressource1 Online-Ressource In this thesis, we attempt to build a numerical model that predicts the traction forces and the actin distribution in osteoblasts when they interact with substrates of different characteristics, where the effects of external electric field are addressed. Our model is based on a bio-chemo-mechanical model that has been widely used in cell mechanics, which possesses many advantages and has been widely applied to simulate two and three dimensional cells in interaction with various substrates.<eng> vorgelegt von Thanh Duy Truong GutachterInnen: Ursula van Rienen (Universität Rostock, Institut für Allgemeine Elektotechnik) ; Barbara Nebe (Universitätsmedizin Rostock, Zentrum für Medizinische Forschung, Arbeitsbereich Zellbiologie) ; José Manuel García Aznar (Universidad de Zaragoza, Multiscale in Mechanical and Biological Engineering) Dissertation Universität Rostock 2018 530 610.28 610 WD 2300 WD 2600 44.09 http://purl.uni-rostock.de/rosdok/id00002516 https://doi.org/10.18453/rosdok_id00002516 https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002516-0 https://d-nb.info/1293657409/34 Computational investigation of the response of osteoblasts in interaction with substrate under effects of electric field exposure--(DE-627)1027617689 urn:nbn:de:gbv:28-rosdok_id00002516-0 doi: 10.18453/rosdok_id00002516 oclc: 1135657199 ppn: (DE-627)1671390156