Qualitative effect of tissue heterogeneity and modiolus porosity on the transmembrane potential of type-1 spiral ganglion neurons in the human cochlea: a simulation study Sriperumbudur, Kiran Kumar , 1976- (VerfasserIn) Rienen, Ursula van , 1957- (AkademischeR BetreuerIn) Pau, Hans-Wilhelm , 1949- (AkademischeR BetreuerIn) Gummer, Anthony W. (AkademischeR BetreuerIn) Spors, Sascha Michael , 1972- (AkademischeR BetreuerIn) Universität Rostock (Grad-verleihende Institution) Universität Rostock Fakultät für Informatik und Elektrotechnik (Grad-verleihende Institution) Text theses Text Hochschulschrift 2018 2018 eng electronic resourceremoteComputermedienOnline-Ressource1 Online-Ressource Electric stimulation of auditory nerve by cochlear implants has been a successful clinical intervention to treat the sensorineural deafness. However, various micro-anatomical factors have not been considered in the state of the art models while studying the interaction between the applied electric field and the auditory nerve. The present finite element modeling study suggests that the modiolus porosity and tissue heterogeneity significantly alter the electric field distribution in the Rosenthal’s canal and thereby affect the cochlear implant functionality.<eng> vorgelegt von Kiran Kumar Sriperumbudur GutachterInnen: Ursula van Rienen (Universität Rostock, Institut für Allgemeine Elektrotechnik) ; Hans Wilhelm Pau (Universitätsmedizin Rostock, Klinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie "Otto Körner") ; Anthony Gummer (Universitätsklinikum Tübingen, Hals-Nasen-Ohren-Klinik) ; Sascha Spors (Universität Rostock, Institut für Nachrichtentechnik) Dissertation Universität Rostock 2019 621.3 617.8 610 XC 4076 ZN 3240 44.94 http://purl.uni-rostock.de/rosdok/id00002456 https://doi.org/10.18453/rosdok_id00002456 https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002456-0 https://d-nb.info/1293656305/34 Qualitative effect of tissue heterogeneity and modiolus porosity on the transmembrane potential of type-1 spiral ganglion neurons in the human cochlea--(DE-627)1666371548 urn:nbn:de:gbv:28-rosdok_id00002456-0 doi: 10.18453/rosdok_id00002456 oclc: 1135324036 ppn: (DE-627)1665994509