@Book{791606627,
author="Supe, Linda",
title="Design and synthesis of 1H-pyrazolo[3,4-b]pyridin-3(2H)-ones and corresponding N-nucleosides: new purine isosters as potential drug-like scaffolds",
year="2014",
abstract="The work is devoted to study synthesis of 1H-pyrazolo[3,4-b]pyridin-3(2H)-ones with potential biological activity. 1H-pyrazolo[3,4-b]pyridin-3(2H)-one derived moieties were afforded using classical approaches involving [3+3] cyclocondensation of enamine fragment-containing heterocycle and bielectrophiles, inverse electron-demand Diels-Alder reaction, palladium-catalyzed C-C coupling reaction. N-nucleosides of purine analogues were synthesized using modified silyl Hilbert-Jones method. Scope and limitations of hydrogenation of pyridine ring of 1H-pyrazolo[3,4-b]pyridin-3(2H)-ones were studied.",
note="vorgelegt von Linda Supe",
note="Rostock, Univ., Mathematisch-Naturwiss. Fak., Diss., 2014",
url="http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0102-2",
url="http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2014-0102-2&pdf",
url="http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2014-0102-2",
language="English"
}