@Book{63043607X,
author="Hildebrandt, Anke",
title="Mutation des mitochondrialen ATP8 Gens verbessert den hepatischen Energiestatus im murinen Modell des akuten septischen Leberversagens",
year="2009",
abstract="We investigated whether a mutation in the ATPase subunit-8 gene exerts effects on the course of endotoxemic acute liver failure in mice. Wildtype and ATP8 mutant mice were challenged with D-galactosamine and E. coli lipopolysaccharide and studied 6 hrs thereafter. Induction of endotoxemic liver failure provoked marked liver damage, a drop of total adenosine nucleotide level and an increased malondialdehyde production. In contrast, ATP levels in livers ATP8 mutants remained significantly higher. As a net result, ATP8 mutant mice showed lower transaminase release and better survival rate.",
note="vorgelegt von Anke Hildebrandt",
note="Rostock, Univ., Med. Fak., Diss., 2010",
note="Online-Ausg.:",
note="[Online-Ausg.]",
note="Reproduktion 2010 [Online-Ausg.] Online-Ausg.: |2010||||||||||",
note="Langzeitarchivierung gew{\"a}hrleistet pdager",
url="http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2010-0091-5",
url="http://rosdok.uni-rostock.de/resolve?urn=urn:nbn:de:gbv:28-diss2010-0091-5&pdf",
url="http://nbn-resolving.de/urn:nbn:de:gbv:28-diss2010-0091-5",
url="http://d-nb.info/1007140712/34",
url="http://rosdok.uni-rostock.de/metadata/rosdok_disshab_000000000458",
language="German"
}