@Book{1950629082, author="Welzen, Matti van", title="Accessible tools for biomolecular data analysis using large-scale knowledge graphs", year="2024", address="Rostock", abstract="The interpretation of biomolecular data is often challenging due to the heterogeneity in the structural and functional organization of biological systems. In this thesis, I created knowledge graphs of disease processes, published as interactive Disease Maps, and developed new tools for their analysis. I present (i) the Atlas of Inflammation Resolution (AIR), (ii) the two-dimensional enrichment analysis (2DEA) as a novel network-based enrichment approach, (iii) the Sarcopenia Map linking gastrointestinal diseases and sarcopenia, and (iv) the MASLD Map investigating steatotic liver diseases.", school="Universit{\"a}t Rostock", note="vorgelegt von Matti van Welzen", note="GutachterInnen: Olaf Wolkenhauer (Universit{\"a}t Rostock) ; Dirk Repsilber ({\"O}rebro University) ; Anna Niarakis (Universit{\'e} Paul Sabatier)", note="Dissertation Universit{\"a}t Rostock 2024", doi="10.18453/rosdok_id00005086", url="https://purl.uni-rostock.de/rosdok/id00005086", url="https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00005086-2", url="https://d-nb.info/1388827212/34", url="https://doi.org/10.18453/rosdok_id00005086", language="English" }