@Book{1877132748,
author="Abt-Becker, Corina",
title="antimicrobial activity of carrier-coupled antisense peptide nucleic acids (PNAs) on streptococci",
year="2023",
address="Rostock",
abstract="The pathogens Streptococcus pneumoniae and Streptococcus pyogenes can cause serious diseases. In this work effective carrier-coupled antisense peptide nucleic acids (PNAs) against S. pneumoniae were identified. The counteranion pyrenebutyrate was investigated for its ability to improve uptake of CPP-PNAs in streptococci. Furthermore, transcriptomic effects of CPP-PNA on streptococci were examined. As Galleria mellonella is an increasingly popular infection model organism, additionally the S. pyogenes specific immune response of the larvae was investigated using a proteomics approach.<eng>",
school="Universit{\"a}t Rostock",
note="vorgelegt von Corina Abt-Becker",
note="GutachterInnen: Nadja Patenge (Institut f{\"u}r Medizinische Mikrobiologie, Virologie und Hygiene, Universit{\"a}t Rostock) ; Mirko Basen (Institut f{\"u}r Biowissenschaften, Universit{\"a}t Rostock) ; Ulrike Giemsa (Leibniz-Institut f{\"u}r Nutztierbiologie (FBN) Dummerstorf)",
note="Dissertation Universit{\"a}t Rostock 2023",
doi="10.18453/rosdok_id00004509",
url="https://purl.uni-rostock.de/rosdok/id00004509",
url="https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004509-4",
url="https://d-nb.info/131537935X/34",
url="https://doi.org/10.18453/rosdok_id00004509",
language="English"
}