@Book{1872125352,
author="Albony, Hasan",
title="Phosphoproteome analysis of the near-haploid cell line HAP1 reveals phosphorylation events originating from PDZ-binding kinase/T-LAK cell-originated protein kinase (PBK/TOPK)",
year="2021",
address="Rostock",
abstract="PBK is a serine/threonine kinase. During mitosis, PBK phosphorylates the inter-zinc finger linker sequence (TGEKP) of hundreds of C2H2 zinc finger proteins and liberates these transcription factors from the condensing chromatin. This study aimed to investigate PBK-dependent phosphorylation events by analyzing the phosphoproteome of both wild and PBK knockout HAP1 cells. The analysis identified candidates belong to DNA- and RNA binding proteins (ADNP and FUBP1) or dynamic regulators of cell organelles (MARCKS and PGRMC1).<eng>",
school="Universit{\"a}t Rostock",
note="vorgelegt von Hasan Albony",
note="GutachterInnen: Hans-J{\"u}rgen Thiesen (Institut f{\"u}r Immunologie, Universit{\"a}t Rostock) ; Christopher Gerner (Fakult{\"a}t f{\"u}r Chemie, Universit{\"a}t Wien) ; Hugo Murua Escobar (Medizinische Klinik III, Universit{\"a}t Rostock)",
note="Dissertation Universit{\"a}t Rostock 2022",
doi="10.18453/rosdok_id00004478",
url="https://purl.uni-rostock.de/rosdok/id00004478",
url="https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00004478-9",
url="https://d-nb.info/1313002321/34",
url="https://doi.org/10.18453/rosdok_id00004478",
language="English"
}