@Book{1745155198, author="Thiele, Frauke", title="Optimisation of stem cell based approaches towards cardiac regeneration", year="2019", address="Rostock", abstract="Aberrant behaviour of resident cells causes several illnesses. Among them, cardiovascular diseases are the leading cause of death in the western world. The human heart possesses only negligible myocardial regeneration capacity after a myocardial infarction, thus, it cannot compensate the massive cell loss self-reliantly. The thesis addresses the optimization of different cell biological approaches for enrichment of cardiac subtypes. Moreover, the thesis demonstrates different genetic manipulation strategies (DNA-, mRNA- and microRNA-based) for an efficient modulation of cell fate.", school="Universit{\"a}t Rostock", note="vorgelegt von Frauke Thiele geb. Hausburg", note="GutachterInnen: Robert David (Universit{\"a}tsmedizin Rostock, Klinik und Poliklinik f{\"u}r Herzchirurgie) ; Reinhard Schr{\"o}der (Universit{\"a}t Rostock, Institut f{\"u}r Biowissenschaften) ; Stefan Brunner (LMU M{\"u}nchen, Medizinische Klinik und Poliklinik 1)", note="Dissertation Universit{\"a}t Rostock 2020", doi="10.18453/rosdok_id00002896", url="http://purl.uni-rostock.de/rosdok/id00002896", url="https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002896-1", url="https://d-nb.info/1293662240/34", url="https://doi.org/10.18453/rosdok_id00002896", language="English" }