@Book{1662422075, author="Masloboy, Axel", title="Two Zona Pellucida vaccines expressed in different plant expression systems for spaying mammals", year="2018", address="Rostock", abstract="This is a concept study of designing two contraceptive vaccines, expressing them in different plant expression systems und testing their efficacy. As antigens fertilization-relevant Zona Pellucida proteins were used. Stable transformed pea seeds, tobacco seeds, tobacco leaves and carrot cells show vaccine accumulation. A transient expression system was used for producing and characterizing the vaccines. The vaccines elicited a strong immune response, which reduced offspring of BALB/c mice up to 52 {\%}.", school="Universit{\"a}t Rostock", note="vorgelegt von Axel Masloboy", note="GutachterInnen: Inge Broer (Universit{\"a}t Rostock, Agrar- und Umweltwissenschaftliche Fakult{\"a}t, Agrobiotechnologie) ; Ann Depicker (Universiteit Gent, VIB)", note="Dissertation Universit{\"a}t Rostock 2018", doi="10.18453/rosdok_id00002426", url="http://purl.uni-rostock.de/rosdok/id00002426", url="https://nbn-resolving.org/urn:nbn:de:gbv:28-rosdok_id00002426-0", url="https://d-nb.info/1293533912/34", url="https://doi.org/10.18453/rosdok_id00002426", language="English" }