@Book{1025372573,
author="Khani, Afsaneh",
title="Investigating the mechanism of a novel glycine-dependent riboswitch and a putative non-coding regulatory RNA in Streptococcus pyogenes",
year="2017",
address="Rostock",
abstract="We investigated gene expression regulation by a putative glycine(Gly) riboswitch located in the 5{\textasciiacutex}-UTR of a SAF protein gene in the S.pyogenes. Gly-dependency was studied using a luciferase reporter gene system. Maximal reporter gene expression happened in the presence of low Gly concentrations. RT-qPCR showed that in the presence of Gly (≥1 mM), expression of the gene was downregulated. Growth in the presence of 0.1 mM Gly led to the production of a full-length transcript. We conclude that the Gly riboswitch in S. pyogenes represses gene expression in the presence of high Gly concentrations.<eng>",
school="Universit{\"a}t Rostock",
note="vorgelegt von Afsaneh Khani aus dem Iran",
note="Dissertation Universit{\"a}t Rostock 2018",
doi="10.18453/rosdok_id00002093",
url="http://rosdok.uni-rostock.de/resolve/urn/urn:nbn:de:gbv:28-diss2018-0087-1",
url="https://nbn-resolving.org/urn:nbn:de:gbv:28-diss2018-0087-1",
url="https://d-nb.info/1293652717/34",
url="https://doi.org/10.18453/rosdok_id00002093",
language="English"
}