@Book{1009595563,
author="P{\"u}gge, Johanna",
title="Adhesive mechanisms of histone-induced neutrophil-endothelium interactions in the muscle microcirculation",
year="2016",
address="Rostock",
abstract="Intravital microscopy of the mouse cremaster microcirculation was used to examine the role of specific adhesion molecules in histone-dependent leukocyte recruitment. Histones type 3 were given locally to the cremaster muscle sack and specific adhesion molecules were blocked by systemic administration of monoclonal antibodies. Extracellular histones 3 induced leukocyte recruitment in a dose-dependent manner. Histone-induced neutrophil rolling is predominately mediated by P-selectin/PSGL-1 interactions, whereas histone-induced leukocyte adhesion is inter alia mediated by Mac-1 and LFA-1.<eng>",
school="Universit{\"a}t Rostock",
note="vorgelegt von Johanna P{\"u}gge",
note="Dissertation Universit{\"a}t Rostock 2017",
url="http://rosdok.uni-rostock.de/resolve/urn/urn:nbn:de:gbv:28-diss2017-0168-6",
language="English"
}